Structural and functional analysis of rRNA methyltransferase fromStaphylococcus aureus
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چکیده
منابع مشابه
Structural and functional insights into the molecular mechanism of rRNA m6A methyltransferase RlmJ
RlmJ catalyzes the m(6)A2030 methylation of 23S rRNA during ribosome biogenesis in Escherichia coli. Here, we present crystal structures of RlmJ in apo form, in complex with the cofactor S-adenosyl-methionine and in complex with S-adenosyl-homocysteine plus the substrate analogue adenosine monophosphate (AMP). RlmJ displays a variant of the Rossmann-like methyltransferase (MTase) fold with an i...
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15 صفحه اولSubstrate binding analysis of the 23S rRNA methyltransferase RrmJ.
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ژورنال
عنوان ژورنال: Acta Crystallographica Section A Foundations of Crystallography
سال: 2011
ISSN: 0108-7673
DOI: 10.1107/s0108767311089069